Liste complète des publications

PUBLICATIONS SÉLECTIONNÉES

IL-15 Prevents the Development of T-ALL from Aberrant Thymocytes with Impaired DNA Repair Functions and Increased NOTCH1 Activation. Nandi M. et al. Cancers 2023

Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. Baran N et al. Nature Communication. 2022

PU.1 - c- Jun interaction is crucial for PU.1 function in myeloid development. Comm Biol, 2022 ​

Monoallelic Heb/Tcf12 deletion reduces the requirement for NOTCH1 hyperactivation in T-cell acute lymphoblastic leukemia. Veiga DFT, Tremblay M et al. Frontiers in Immunology. 2022

Molecular Switches of the Immune System: The E Protein/Id Axis in Hematopoietic Development and Function. Frontiers in Immunology. 2022

Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma. Nature Cancer, 2020

A targetable cue in T-cell malignancy. Gerby B, Hoang T. Blood. 2020 ​

Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation.Da Costa et al. J Exp Clin Cancer Res. 2019

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Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation. J Clin Invest. 2018 

Evolution of AF6-RAS association and its implications in mixed-lineage leukemia. Smith et al. Nat Commun. 2017 

High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells. Gerby et al. J Clin Invest.  2016 
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The LMO2 oncogene regulates DNA replication in hematopoietic cells. Sincennes et al. Proc Natl Acad Sci. 2016 ​

SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells. Gerby et al. PLoS Genet. 2014
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Genetic interaction between Kit and Scl. Blood. 2013

The T-ALL paradox in cancer. Hoang T, Hoang T. Nat Med. 2010

Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes. Tremblay et al. Genes Dev. 2010 

Scl regulates the quiescence and the long-term competence of hematopoietic stem cells. Lacombe et al. Blood. 2010 ​

ETO2 coordinates cellular proliferation and differentiation during erythropoiesis. Goardon et al. EMBO J. 2006